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Nortriptyline dosing down to 10 mg/day or 5 with placebo. One of the active drug in study, zuclopenthixol, had been tested in previous Phase I trials of atypical antipsychotic drugs. But the researchers noted that, when taken at high doses, zuclopenthixol can induce side effects that "may have contributed to its unfavorable safety profile" in previous research (Zimmer et al., 2001, p. 1185).
The researchers also observed a higher rate of adverse events among patients taking atypical paroxetine dosage uk antipsychotics compared to patients who received placebo. Among receiving atypical antipsychotics, 18% reported a serious adverse event and non-serious rate of 23% compared to 8% for the patients who received placebo. randomized to atypical antipsychotics were also at least twice as likely to experience buy paroxetine 20 mg adverse events (5 vs. 1.57%, P=0.05).
In contrast, the adverse events among patients taking placebo were very rare. In the overall sample of 6,534 participants, there were only six serious or non-serious adverse events reported within the where to buy paroxetine online 24 pharmacy online usa international shipping months after study
Precio del acido valproico en mexico entry. There were also two serious cardiovascular events and one other serious event. The number of events reported within the previous year was similar for the 2,000 plus patients who completed the study (3) and for 1,600 patients who entered the study prior to December 2002 (1).
Conclusion
In this first study comparing different antipsychotic treatments, the participants in a randomized, double-blind, controlled study experienced more adverse events with risperidone compared to placebo. However, there were far fewer adverse events associated with zuclopenthixol use compared to other antipsychotic medications. More research is warranted to examine if there are other potential risks of zuclopenthixol, than the rare side effects reported in the study, as well overall effects across these antipsychotic drugs.
(featured image source: https://www.flickr.com/photos/wendyhull/2795371364/ )
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