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Vasotec tablets composition of 10 parts chloroform and 4 of ether. A portion the chloroform content is converted to water with an addition of potassium chlorate. The ether is evaporated and chloroform precipitates out as a grey crystalline substance which is dissolved in water to the level of 3 4 parts per 000 milliliters dry weight. The ether content should be from 25 to 40 parts per million. Dilute aqueous ethyl alcohol is used as a solvent and the solution prepared may be used to make the chloroform tablets compositions in a number of compositions.
Example 21
Lysine Hydrochloride in Parenteral Form for Treatment or Therapy
1. In a pharmaceutical composition containing an antiscrapid agent, the sulfate moiety may be present at from 5 to 20 parts by volume. In an alternative, the sulfate moiety may be added
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2. In a pharmaceutical composition containing an antiscrapid agent, the sulfate moiety may be present at from 5 to 30 parts by volume. In an Atorvastatin $412 $75 - Per pill alternative, the sulfate moiety may be added at from 10 to 20 parts by volume.
3. In a pharmaceutical composition containing an antiscrapid agent, the sulfate moiety may be present at from 15 to 30 parts by volume. In an alternative, the sulfate moiety may be added at from 30 to 50 parts by volume.
4. In combination, the antiscrapid agent ethyl chloride and methylethyl ether are present in the amount of 100 parts by volume while the sulfur is present at 150 parts by volume.
5. In the course of preparing pharmaceutical composition, the sulfate moiety is present in the amount of 50 to 60 parts by volume whereas the sulfur is present at 60 to 65 parts by volume. The total amount of a salt the antiserum is approximately 15 to 17 parts by volume and the antiserum is added to mixture in the proportions indicated.
6. The pharmaceutical composition with antiserum is mixed the pharmaceutical composition containing antiscrapid agent by immersion in sterile 0.1 percent sodium chloride solution, and injected intravenously via a suitable syringe. The contents of injector, having been injected with a pharmaceutically inert solution, have then been returned to the sterile environment of a laboratory.
EXAMPLES
In a preferred embodiment of parenteral formulation containing an antibiotic sulfate antiserum, a parenteral tablet may be constructed using the following formula (in which A 1 =5, B 2 =10, C 3 =2 and D =10, R 2 =0.05):
Tablets, Formulation 1
A B C D 10 0.025 mL 0.05 mg 25 10 0.025 mL 0.15 mg 40 10 0.025 mL 0.23 mg 50 10 0.025 mL 0.39 mg 60 15 0.025 mL 5.0 mg 70 20 0.025 mL 1.2 mg 80 30 0.025 mL 0.94 mg 0.085 L 0.125 mL
Tablets, Formulation 2
A B C D 20 0.5 mL 0.05 mg 30 40 10 0.025 mL 0.15 mg 50 10 0.5 mL 0.03 mg 60 10 0.025 mL 0.15 mg 70 20 0.5 mL 0.25 mg 80 30 0.066 mL 0.14 mg 90 40 0.5 mL 0.069 mg 100 50 0.067 mL 0.11 mg 120 70 0.5 mL 0.10 mg 130 80 0.068 mL 0.12 mg 140 90 0.5 mL 0.11 mg 150 10 0.5 mL 0.13 mg 160 10 0.5 mL 0.13 mg 170 20 0.5 mL 2
A further pharmaceutical tablet composition may contain antibiotics sulfate in form of an insoluble or immiscible gel and for such composition, the tablets (Tablets, Formulation 3) may form one or more layers of which a thin layer on
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Tablets, Formulation 4
A B C D 30 10 0.02 mg 0.05 5,0 20 10 0.02 mg 2,5 30 - 5 0.02 mg 2,5 30 10 - 0.02 mg 2,5 50 10 - 20 0.02 mg 1,5 50 5 - 40 10 100 50 5 mg - 40 10 50 0,1
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